The distance between Knoxville to Santee / Santee Lakes KOA Journey is 523 Mi by road. You can also find the distance from Knoxville to Santee / Santee Lakes KOA Journey using other travel options like bus, subway, tram, train and rail. Apart from the trip distance, refer
Directions from Knoxville to Santee / Santee Lakes KOA Journey for road driving directions!